TisXell Bi-Axial Bioreactor

Bi-Axial

Rotating

Bioreactor

bioreactor

TisXell Bi-Axial Rotating System distinctive design offers a nurturing culture environment to cells and tissues.  Its unique bi-directional revolution simulates nature’s biological ecosphere, accelerating homogenous cell growth throughout 3D tissue constructs.

Benefits from using the TisXell Bi-Axial Bioreactor

  • Accelerates cell growth, differentiation and cell proliferation, mimicking native extracellular matrix (ECM)
  • Supports homogenous cell culture at the surface and core of 3D scaffolds
  • Maintains functionality and viability of tissue constructs
  • Reduces formation of necrotic neo-tissue that interferes with subsequent implantation process
  • Promotes integration of implants with surrounding tissue and supports the structural integrity in regeneration of tissues and organs
  • Suitable for many application fields such as Cell Therapy, Tissue Engineering, Biomaterial Testing, Toxicology/Drug Development and Personalized Medicine
  • Highly Customizable for any requirements and applications

Fig 1. Up to 10x cells expansion achievable! Extension of two days in growth proliferation was seen from Rotating chamber as compared to Static chamber in cell lines we have tested on. Results may differ from the manipulation of cell seeding population with fixed volume of media and chamber size.

Fig 2. TisXell (blue) has shown an increased in cell proliferation as compared to other culture systems

The levels of Col 2 and Agg were found to be much higher in the biaxial rotary environment. Clearly indicating that cells grown under biaxial rotary condition retain their native chondrogeneic markers better compared to static condition. 

The levels of Col 2 and Agg were found to be much higher in the biaxial rotary environment. Clearly indicating that cells grown under biaxial rotary condition retain their native chondrogeneic markers better compared to static condition. 

With biaxial rotary environment (B) cells were in homogeneous single cell population

The TisXell Bioreactor is a Bi-Axial rotating bioreactor specifically designed to provide a favorable environment for high growth and high proliferation of cell cultures

A bioreactor that has been designed to rotate simultaneously in two independent axes, allowing it to Spin and Tumble simultaneously. The gyroscopic movement leads to an improved flow of fluids within the bioreactor for accelerated cell proliferation

Bi-axial rotation, Uniaxial spin or tumble, Swing modes. These modes can be run individually or programmed to run progressively

Accelerates cell growth, differentiation and cell proliferation, mimicking native extracellular matrix (ECM). Supports homogenous cell culture at the surface and core of the 3D scaffolds and maintains functionality and viability of tissue constructs.
Reduces formation of necrotic neo-tissue that interferes with subsequent implantation process as well as Promotes integration of implants with surrounding tissue and support the structural integrity in regeneration of tissues and organs

The TisXell is available direction from Quintech Life Sciences webpage. Feel free to request for a quotation.

The TisXell Bi-Axial Bioreactor has a specifically designed spherical chamber that sits on a bracket that allows it to both Spin on the horizontal and vertical axis. This allows improved medium mass transfer to and from the center of the chamber.